project aims

In 2016 the project moved to the School of Medicine and Pharmacy and School of Dentistry of the University of Rwanda. One of the remarkable findings of this research thus far is that a substantial amount of primar bone—formed in childhood and never remodeled—remains in the adult skeleton as bone increments called lamellae. Because bones and teeth maintain a mineralized secretory record of their growth as lamellar incremental lines, these lamallae, when calibrated in real time using teeth from the same individual, reveal growth rate variability at timescales ranging from months to well over one decade (15 years is the current maximum).

66Zn/88Sr ratio

Annual rainfall

0,45

0,4

0,35

0,3

0,25

0,2

0,15

10

8

6

4

2

1981

1983

1985

1987

1989

1991

1993

1995

Primary lamellar bone from a 26 year old subsistence fisherman from the Lake Chilwa region in southern Malawi was evaluated with our simultaneous laser ablation inductively coupled plasma mass spectrometer, from which a total of 64 elements were identified. We plotted regional rainfall data corresponding to the 15 years represented in his lamellae, deposited during 1981-1996.  66Zn/88Sr roughly correspond with rainfall, suggesting that the metabolic flux of materials is sensitive to environmental factors and is comparable to variation in trace elements expected by physiological ecologists.

Bantu Bone and Tooth Biology

We presently operate an NSF-funded program to obtain bone and tooth samples from University of Malawi College of Medicine cadavers for which there exist extensive life histories.  Because their bones and teeth maintain a mineralized secretory record of their growth as incremental lines, these increments, when calibrated in real time, reveal growth rate variability at timescales ranging from several weeks to one year.

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New York University College of Dentistry Senckenberg Research Institute

Dr. Timothy G. Bromage

Hard Tissue Research Unit

Department of Biomaterials & Biomimetics

New York University College of Dentistry

345 East 24th Street

New York, NY  10010-4086

USA

Dr. Friedemann Schrenk

Senckenberg Gesellschaft für Naturforschung

Sektion Paläoanthropologie

Senckenberganlage 25

60325 Frankfurt

Deutschland

 

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New York University College of Dentistry
Senckenberg Research Institute
Stoichy logo © F&H 2016 Human Biomics Laboratory logo © F&H 2016
Logo Paleobiomics © F&H 2016
Paleobiomics logo © F&H 2016
New York University College of Dentistry Senckenberg Research Institute
Stoichy logo © F&H 2016 Human Biomics Laboratory logo © F&H 2016

We presently operate an NSF-funded program to obtain bone and tooth samples from University of Malawi College of Medicine cadavers for which there exist extensive life histories.  Because their bones and teeth maintain a mineralized secretory record of their growth as incremental lines, these increments, when calibrated in real time, reveal growth rate variability at timescales ranging from several weeks to one year.

In 2016 the project moved to the School of Medicine and Pharmacy and School of Dentistry of the University of Rwanda. One of the remarkable findings of this research thus far is that a substantial amount of primar bone—formed in childhood and never remodeled—remains in the adult skeleton as bone increments called lamellae. Because bones and teeth maintain a mineralized secretory record of their growth as lamellar incremental lines, these lamallae, when calibrated in real time using teeth from the same individual, reveal growth rate variability at timescales ranging from months to well over one decade (15 years is the current maximum).

Paleobiomics logo © F&H 2016 Stoichy logo © F&H 2016
Human Biomics Laboratory logo © F&H 2016
Logo Paleobiomics © F&H 2016
Paleobiomics logo © F&H 2016